Growing up in the rural town of Pattiveeranpatti, Tamilnadu, India, Dr. Sadayappan was destined to be a coconut farmer. However, with guidance from his parents, he decided to take a very different path as a scientist. Based on his fascination with plant life on the farm, he would go on to receive his undergraduate degree in Botany. Armed with innate academic ability and a thirst for more knowledge, he continued his graduate and doctoral studies, taking a long road leading, finally, to the post of Professor of Internal Medicine at University of Cincinnati. With his expertise in molecular cardiology, Sadayappan established his lab in 2009, and since then, he has been committed to investigating the regulatory, structural and functional role(s) of the striated muscle protein, myosin binding protein-C, in health and disease.
Establish an integrative, multidisciplinary research, training and education program dedicated to solving the intractable problems associated with cardiovascular and skeletal muscle biology.
Sadayappan Lab provides opportunity for graduate students to do lab rotation, who are from integrated biology and physiology programs.
We will examine the association between cardiac myosin binding protein-C degradation and cardiac dysfunction, leading to the development of potential cardioprotective .....
The long-term goal of Sadayappan lab is to delineate the role of myosin binding protein-C regulation and function in the heart. For more information and to access all our publications,
Sakthivel Sadayappan, Ph.D., MBA
Professor of Internal Medicine
Dr. James F. Heady Endowed Chair in Medicine
Executive Director, Center for Cardiovascular Research
Associate Director of Basic Research, Division of Cardiovascular Health and Disease
University of Cincinnati College of Medicine
Cardiovascular Center, Rm 4935
231 Albert Sabin Way
Cincinnati, OH 45267-0575, USA
Phone : +1 513-558-7498
Email : email@example.com